Tissue microarray can be used to study the expression of gene and protein, and it has an important role in studying the expression of disease-related gene and protein, molecular diagnosis, evaluating the effect of treatment and screening of new drugs.
构建不同类型的组织芯片并以此研究基因和蛋白质表达情况,对人类后基因组学的研究与发展,尤其对于认识疾病相关的基因功能和蛋白质变化与分子诊断、评价治疗过程与效果、判断疾病预后以及新药筛选与开发等,都具有重要意义。
参考来源 - 人脑星形细胞肿瘤微血管(AstMV)组织芯片的构建与计算机辅助的AstMV三维重建·2,447,543篇论文数据,部分数据来源于NoteExpress
Establishing rational pharmacokinetic screening models can not only decrease the cost of finding new drugs, but also give a correct evaluation at the beginning of drug research.
建立合理的药动学筛选模型不仅可以降低新药开发的成本,并且可以在新药研究早期对其作出正确的评价。
It is of research and clinical significance to construct effective models of HBV infection for exploring the infection mechanism, finding new therapies and screening new anti-HBV drugs.
如何建立一种有效的HBV感染模型,对于探索其感染机制,寻找有效的防治方法及开展抗hbv药物的筛选都具有重要的科研及临床意义。
Abstract: the use of biological transformation of structural modification of natural drugs is one of the effective ways for screening new natural active compounds.
摘要:利用生物转化对天然药物进行结构修饰,是筛选新的天然活性化合物的有效途径之一。
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